Ann.Nutr.Metab 2008;53(2):91-95. Soyucen, E., Demirci, E., and Aydin, A. Outpatient treatment of propionic acidemia-associated hyperammonemia with N-carbamoyl-L-glutamate in an infant. View abstract. View abstract. View abstract. Mingrone G. Carnitine in type 2 diabetes. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Eur Heart J 1992;13:251-5. Cherchi A, Lai C, Onnis E, et al. 1999;12(1):38-40. View abstract. Opala G, Winter S, Vance C, et al. Cruciani RA, Zhang JJ, Manola J, Cella D, Ansari B, Fisch MJ. Xie, J., Zeng, Q., and Wang, L. The protective effect of L-carnitine on ischemia-reperfusion heart. View abstract. Effects of L-carnitine supplemented total parenteral nutrition on lipid and energy metabolism in postoperative stress. Mov Disord. The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials. View abstract. As stated previously, foods high in sugar and saturated fat have been associated with poor sleep quality and sleep disturbances . [Efficacy of natural vitamin E on oligospermia and asthenospermia: a prospective multi-centered randomized controlled study of 106 cases]. View abstract. L-carnitine supplementation for the management of fatigue in patients with hypothyroidism on levothyroxine treatment: a randomized, double-blind, placebo-controlled trial. Obstet.Gynecol. 2012;13(2):285-293. Hiraoka A, Kiguchi D, Ninomiya T, et al. View abstract. Carnitine metabolism in early stages of Duchenne muscular dystrophy. Association of L- carnitine, propafenone and mexiletine]. J.Altern.Complement Med. Penn, D., Schmidt-Sommerfeld, E., and Pascu, F. Decreased tissue carnitine concentrations in newborn infants receiving total parenteral nutrition. Chen Y, Abbate M, Tang L, Cai G, Gong Z, Wei R, Zhou J, Chen X. L-Carnitine supplementation for adults with end-stage kidney disease requiring maintenance hemodialysis: a systematic review and meta-analysis. View abstract. Drugs Exp Clin Res 1995;21(4):157-159. Amino.Acids 2012;42(5):1783-1792. B., Gokcay, G., Grunewald, S., Guffon, N., Maier, E. M., Morava, E., Geb, S., Schwahn, B., Walter, J. H., Wendel, U., Wijburg, F. A., Muller, E., Kolker, S., and Horster, F. Diagnostic work-up and management of patients with isolated methylmalonic acidurias in European metabolic centres. 2006;7(2):101-109. Cucinotta D, Passeri M, Ventura S, and et al. L-carnitine might increase the effects of warfarin and increase the chances of bruising and bleeding. van Dalen, E. C., Caron, H. N., Dickinson, H. O., and Kremer, L. C. Cardioprotective interventions for cancer patients receiving anthracyclines. View abstract. Penn, D., Schmidt-Sommerfeld, E., and Wolf, H. Carnitine deficiency in premature infants receiving total parenteral nutrition. Indian J Clin Biochem 1992;7:19-21. Jpn Circ.J 1992;56(1):86-94. Phytomedicine. Eur.J Haematol. Ann Neurol 1989;26:456. View abstract. There are several effective supplements that can help you burn body fat. Filipek, P. A., Juranek, J., Nguyen, M. T., Cummings, C., and Gargus, J. J. Do not take extra medicine to make up the missed dose. View abstract. . Kidney Int 38 (1990): 904-11, 4. The GOAL study. 2007;41(3):224-230. Jones, S., Reed, C. A., Vijay, S., Walter, J. H., and Morris, A. Suchitra, M. M., Ashalatha, V. L., Sailaja, E., Rao, A. M., Reddy, V. S., Bitla, A. R., Sivakumar, V., and Rao, P. V. The effect of L-carnitine supplementation on lipid parameters, inflammatory and nutritional markers in maintenance hemodialysis patients. Krahenbuhl S, Reichen J. Carnitine metabolism in patients with chronic liver disease. 2006;142(4):458-460. Low Blood Pressure. Drugs Aging 2003;20:761-7. Carnitine supplementation in diphtheria. View abstract. Nephrol.Dial Transplant 2008;23(3):991-997. Clin Invest Med. 2003;79(2):292-300. J Am Coll Cardiol 1995;26:380-7. Ann N Y Acad Sci 2004;1033:99-107. A., Ebenezer, G. J., Hauer, P., Millar, L., Gould, M., Tran, P., Shikuma, C., Souza, S., and McArthur, J. C. Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection. Does carnitine cause insomnia? Epilepsia 1993;34:184-7. Brevetti, G., Attisano, T., Perna, S., Rossini, A., Policicchio, A., and Corsi, M. Effect of L-carnitine on the reactive hyperemia in patients affected by peripheral vascular disease: a double-blind, crossover study. Rebuzzi AG, Schiavani G, Amico C, and et al. This is a detailed, evidence-based review of the 18 most popular weight loss pills and supplements on the market today. 2010;34(3):295-299. Gurlek, A., Tutar, E., Akcil, E., Dincer, I., Erol, C., Kocaturk, P. A., and Oral, D. The effects of L-carnitine treatment on left ventricular function and erythrocyte superoxide dismutase activity in patients with ischemic cardiomyopathy. Calabrese, V., Cornelius, C., Stella, A. M., and Calabrese, E. J. Clin Drug Invest 1996;11(2):90-96. Monaldi Arch.Chest Dis 2007;68(2):110-114. Prolonged oral L-carnitine substitution increases bicycle ergometer performance in patients with severe, ischemically induced cardiac insufficiency. L-Carnosine (Fig. 2016;63(10):885-95. Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease. A double-blind randomized study. Int J Clin Pharmacol Res 1990;10:355-60. View abstract. Med.Sci Monit. View abstract. Applies to levocarnitine: capsule, capsule liquid filled, solution, tablet. View abstract. A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia. View abstract. Am J Med 2001;110:616-22.. View abstract. Seattle, WA: University of Washington, Seattle;1993. I noticed very sensitive teeth and gums for awhile, but seems to have . Talenezhad N, Mohammadi M, Ramezani-Jolfaie N, Mozaffari-Khosravi H, Salehi-Abargouei A. Fertil.Steril. Effects of propionyl-L-carnitine on peripheral arterial obliterative disease of the lower limbs: a double-blind clinical trial. Hart AM, Wilson AD, Montovani C, et al. View abstract. The effect of carnitine in patients using artificial pacemakers. De Ritis G, Picardo S, Brancadoro D, and et al. Zhou, X., Liu, F., and Zhai, S. Effect of L-carnitine and/or L-acetyl-carnitine in nutrition treatment for male infertility: a systematic review. View abstract. View abstract. Heil, S. G., Hogeveen, M., Kluijtmans, L. A., van Dijken, P. J., van de Berg, G. B., Blom, H. J., and Morava, E. Marfanoid features in a child with combined methylmalonic aciduria and homocystinuria (CblC type). Biolo, G., Stulle, M., Bianco, F., Mengozzi, G., Barazzoni, R., Vasile, A., Panzetta, G., and Guarnieri, G. Insulin action on glucose and protein metabolism during L-carnitine supplementation in maintenance haemodialysis patients. Changes in lipid pattern. View abstract. Yang SK, Xiao L, Song PA, Xu X, Liu FY, Sun L. Effect of L-carnitine therapy on patients in maintenance hemodialysis: a systematic review and meta-analysis. Metabolic rates vary by individual. Weinhandl, E. D., Rao, M., Gilbertson, D. T., Collins, A. J., and Pereira, B. J. Guan, Y., Zheng, X. M., Yang, Z. W., and Li, S. W. [Protective effects of L-carnitine upon testicular ischemia-reperfusion damage in rats]. J Cancer Res.Clin Oncol. Fan, J. P., Kim, H. S., and Han, G. D. Induction of apoptosis by L-carnitine through regulation of two main pathways in Hepa1c1c 7 cells. Brand names: Carnitor, L-Carnitine View abstract. L-Carnosine - not to be confused with the popular supplement, L-carnitine - is a highly effective anti-aging nutrient that possesses powerful antioxidant, free radical scavenging and neurotransmitter properties. Antioxidants may fight both inflammation and oxidation in the body. View abstract. Agarwal A, Sengupta P, Durairajanayagam D. Role of L-carnitine in female infertility. Clin Ter. View abstract. Nutrients 2018;10(2). J Postgrad Med 1999;45(2):38-41. Clin Endocrinol (Oxf) 2016;84(6):851-7. View abstract. View abstract. J Dermatol.Sci 2007;48(2):141-144. J Clin Lipidology 2012;6:150-158. Jpn Heart J 1984;25(4):587-597. Nausea Diarrhea Vomiting Skin rash Less common side effects of Garcinia cambogia include: Mania/psychosis [ 88, 89, 90, 91, 92] Hallucinations, delusions, and impaired coordination [ 93] Heart problems (irregular heart rate, heart muscle damage, and heart failure) [ 94, 95] Serious muscle damage (rhabdomyolysis) [ 96, 97, 98] A randomized, double-blind, placebo-controlled trial of L-carnitine in suspected acute myocardial infarction. Maestri, A., De Pasquale, Ceratti A., Cundari, S., Zanna, C., Cortesi, E., and Crino, L. A pilot study on the effect of acetyl-L-carnitine in paclitaxel- and cisplatin-induced peripheral neuropathy. Martina, B., Zuber, M., Weiss, P., Burkart, F., and Ritz, R. [Anti-arrhythmia treatment using L-carnitine in acute myocardial infarct]. The main dietary sources of L-carnitine are meat, fish and some other animal products, such as milk. Yano J, Kaida Y, Maeda T, et al. O'Donnell, J., Finer, N. N., Rich, W., Barshop, B. A., and Morrow, G. R. Pharmacologic treatment of cancer-related fatigue. Riva R, Albani F, Gobbi G, et al. Sci Rep. 2016;6:19188. View abstract. Naturally produced in the body, acetyl-L-carnitine is also widely available in drugstores, supermarkets and health food catalogs as a . It can cause nausea, vomiting, stomach pain, weakness, and chest pain (angina). A bidimensional echocardiographic study]. Zeitschrift fr Orthomolekulare Medizin 2009;7(3):22-24. Zhonghua Er.Ke.Za Zhi. View abstract. Endocr.J 2010;57(9):777-786. 2007;31(11):1414-1419. Valcour, V., Yeh, T. M., Bartt, R., Clifford, D., Gerschenson, M., Evans, S. R., Cohen, B. Yet, there are a few known side effects that include agitation, insomnia and nausea. 2010;30(4):233-239. Exp.Diabetes Res. View abstract. 2009;25(9):2223-2228. View abstract. [L-carnitine: safe and effective for asthenozoospermia]. Metabolism 2009;58(11):1618-1623. Li, Z., Gu, R. H., Liu, Y., Xiang, Z. Q., Cao, X. R., Han, Y. F., Zhang, X. S., and Wang, Y. X. Curative effect of L-carnitine supplementation in the treatment of male infertility. Diabetes Nutr Metab Clin Exp 1992;5(3):175-181. Int.J Cardiol. View abstract. L-carnitine is LIKELY SAFE when taken by mouth for up to 12 months, and when used as an injection, with the approval of a healthcare provider. O'Brien, D., Chunduri, P., Iyer, A., and Brown, L. L-carnitine attenuates cardiac remodelling rather than vascular remodelling in deoxycorticosterone acetate-salt hypertensive rats. L-carnitine may increase the risk of seizures in those with epilepsy. Pola P, Tondi P, Dal Lago A, and et al. Jing, L., Zhou, L. J., Li, W. M., Zhang, F. M., Yuan, L., Li, S., Song, J., and Sang, Y. Carnitine regulates myocardial metabolism by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha) in alcoholic cardiomyopathy. Effect of L-carnitine on health-related quality of life in patients with liver cirrhosis. Safarinejad, M. R., Hosseini, S. Y., and Kolahi, A. Lee, N. C., Tang, N. L., Chien, Y. H., Chen, C. A., Lin, S. J., Chiu, P. C., Huang, A. C., and Hwu, W. L. Diagnoses of newborns and mothers with carnitine uptake defects through newborn screening. View abstract. View abstract. Newer research illustrates the potential benefits of carnitines different forms, which may be used for various conditions, including heart and brain diseases (22, 23). Orlando G and Rusconi C. Oral L-carnitine in the treatment of chronic cardiac ischaemia in elderly patients. Nutr.Res. Campos Y, Arenas J. 2004;97(2):c41-c48. Gecele M, Francesetti G, and Meluzzi A. Acetyl-L-carnitine in aged subjects with major depression: clinical efficacy and effects on the circadian rhythm of cortisol. View abstract. Golper, T. A., Wolfson, M., Ahmad, S., Hirschberg, R., Kurtin, P., Katz, L. A., Nicora, R., Ashbrook, D., and Kopple, J. D. Multicenter trial of L-carnitine in maintenance hemodialysis patients. View abstract. View abstract. Reprod.Biomed.Online. View abstract. Feillet, F., Ogier, H., Cheillan, D., Aquaviva, C., Labarthe, F., Baruteau, J., Chabrol, B., de, Lonlay P., Valayanopoulos, V., Garnotel, R., Dobbelaere, D., Briand, G., Jeannesson, E., Vassault, A., and Vianey-Saban, C. [Medium-chain acyl-CoA-dehydrogenase (MCAD) deficiency: French consensus for neonatal screening, diagnosis, and management]. Impact of L-carnitine on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled trials. BMC Cardiovasc Disord. Moradi, M., Moradi, A., Alemi, M., Ahmadnia, H., Abdi, H., Ahmadi, A., and Bazargan-Hejazi, S. Safety and efficacy of clomiphene citrate and L-carnitine in idiopathic male infertility: a comparative study. J Am.Board Fam.Med. Jacobs, P. L., Goldstein, E. R., Blackburn, W., Orem, I., and Hughes, J. J. Glycine propionyl-L-carnitine produces enhanced anaerobic work capacity with reduced lactate accumulation in resistance trained males. View abstract. Bjornsson, E. Hepatotoxicity associated with antiepileptic drugs. Follow all directions on your medicine label and package. Effect of L-carnitine on human immunodeficiency virus-1 infection-associated apoptosis: a pilot study. Yet, there are a few known side effects that include agitation, insomnia and nausea. G Ital Cardiol 1983;13(11):291-294. Information from this source is evidence-based and objective, and without commercial influence. In an eight-week study in 38 women who exercised four times per week, there was no difference in weight loss between those who took L-carnitine and those who didnt (24). Korean J.Nutrition 2007;40(7):630-638. Fortin, G., Yurchenko, K., Collette, C., Rubio, M., Villani, A. C., Bitton, A., Sarfati, M., and Franchimont, D. L-carnitine, a diet component and organic cation transporter OCTN ligand, displays immunosuppressive properties and abrogates intestinal inflammation. View abstract. A 1-year controlled trial of acetyl-l-carnitine in early onset AD. It is usually taken in doses from 1000 to 2000 milligrams per day . J Inherit.Metab Dis 9-10-2010; View abstract. View abstract. B., Burlina, A. P., Dixon, M., Duran, M., Goodman, S. I., Koeller, D. M., Muller, E., Naughten, E. R., Neumaier-Probst, E., Okun, J. G., Kyllerman, M., Surtees, R. A., Wilcken, B., Hoffmann, G. F., and Burgard, P. Guideline for the diagnosis and management of glutaryl-CoA dehydrogenase deficiency (glutaric aciduria type I). View abstract. Side Effects. Marconi C, Sassi G, Carpinelli A, Cerretelli P. Effects of L-carnitine loading on the aerobic and anaerobic performance of endurance athletes. Tanner, L. M., Nanto-Salonen, K., Rashed, M. S., Kotilainen, S., Aalto, M., Venetoklis, J., Niinikoski, H., Huoponen, K., and Simell, O. Carnitine deficiency and L-carnitine supplementation in lysinuric protein intolerance. 2007;18(8):533-540. View abstract. 2008;10(5):818-830. Schoderbeck M, Auer B, Legenstein E, et al. View abstract. Tarighat, Esfanjani A., Mahdavi, R., Ebrahimi, Mameghani M., Talebi, M., Nikniaz, Z., and Safaiyan, A. Avoid taking ALCAR too late in the day, as it can cause insomnia in some people. Pediatr.Neonatol. Micic S, Lalic N, Djordjevic D, et al. View abstract. Jeulin C, Lewin LM. Bohmer, T., Boen, A., and Hoymork, S. C. Valproate-induced hyperammonemic encephalopathy, rapidly improved by i.v. Support Care Cancer. Chen N, Yang M, Zhou M, Xiao J, Guo J, He L. L-carnitine for cognitive enhancement in people without cognitive impairment. Sima AAF, Calvani M, Mehra M, et al. Intern.Med 2010;49(16):1717-1725. This differs from supplements like caffeine or creatine, which can directly enhance sports performance. Fietta, P. and Manganelli, P. Carnitine: a therapeutic option for childhood psoriatic onycho-pachydermo-periostitis (POPP). 2004;34(6):615-623. Endocr J 2018;65(5):521-6. A. View abstract. View abstract. Kaviani, M., Nourshahi, M., and Shokoohi, F. The effects of acute L-carnitine administration on ventilatory breakpoint and exercise performance during incremental exercise. Drug class: Nutraceutical products. Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo-controlled, crossover study. Carnitine and physical exercise. Trk Kardiyol Dern Ars -Arch Turk Soc Cardiol. Am.J Clin Oncol. Drugs 1999;58:479-87. View abstract. J Inherit.Metab Dis 1-7-2008; View abstract. Wadman, R. I., Bosboom, W. M., van der Pol, W. L., van den Berg, L. H., Wokke, J. H., Iannaccone, S. T., and Vrancken, A. F. Drug treatment for spinal muscular atrophy types II and III. The use of CAM by women suffering from nausea and vomiting during pregnancy. 2010;7:39. View abstract. A., and Farok, M. Assessment of puberty in relation to L-carnitine and hormonal replacement therapy in beta-thalassemic patients. View abstract. Gonzalez-Ortiz, M., Hernandez-Gonzalez, S. O., Hernandez-Salazar, E., and Martinez-Abundis, E. Effect of oral L-carnitine administration on insulin sensitivity and lipid profile in type 2 diabetes mellitus patients. Int J Clin Pharm Res 1982;2(2):143-148. View abstract. Vidal-Casariego A, Burgos-Pelez R, Martnez-Faedo C, Calvo-Gracia F, Valero-Zanuy M, Luengo-Prez LM, Cuerda-Comps C. Metabolic effects of L-carnitine on type 2 diabetes mellitus: systematic review and meta-analysis. Merchant, R., Jain, A., Udani, A., Puri, V., and Kotian, M. L-carnitine in beta thalassemia. Derosa, G., Maffioli, P., Salvadeo, S. A., Ferrari, I., Gravina, A., Mereu, R., D'Angelo, A., Palumbo, I., Randazzo, S., and Cicero, A. F. Sibutramine and L-carnitine compared to sibutramine alone on insulin resistance in diabetic patients. Does left ventricular function improve with L-carnitine after acute myocardial infarction? Cardiology 2006;106(4):215-223. For your body to produce it in sufficient amounts, you also need plenty of vitamin C (4). Journal of New Drugs 1966;6(6):351-353. del Olmo, J. Effects of acute L-carnitine intake on metabolic and blood lactate levels of elite badminton players. L-Carnitine may also be used for purposes not listed in this medication guide. View abstract. Hoffman, J. R., Ratamess, N. A., Gonzalez, A., Beller, N. A., Hoffman, M. W., Olson, M., Purpura, M., and Jager, R. The effects of acute and prolonged CRAM supplementation on reaction time and subjective measures of focus and alertness in healthy college students. Nutr J 2012;11:52. How can you boost your metabolism? 2013 Nov;30(8):742-7. Plasma and urine carnitine concentrations in well-trained athletes at rest and after exercise. Neurology 1996;47:705-11. View abstract. It is not known whether levocarnitine passes into breast milk or if it could harm a nursing baby. View abstract. Lacour B, Di Giulio S, Chanard J, Ciancioni C, Haguet M, Lebkiri B, Basile C, Drueke T, Assan R, Funck-Brentano JL "Carnitine improves lipid anomalies in haemodialysis patients." If you happen to feel nausea, next time just take this supplement with food or take a lesser dose. 2011;18(1):18-22. Pharmacol Res 1998;37(2):115-122. 2008;22(4):1130-1135. View abstract. Carnitor (levocarnitine)." L-carnitine decreases severity and type of fatigue induced by interferon-alpha in the treatment of patients with hepatitis C. Neuropsychobiology 2003;47:94-7. 2005;45(6):343-351. It can cause nausea, vomiting, stomach pain, weakness, and chest pain (angina). L-carnitine has most often been used by adults in doses of 2 grams by mouth daily. Ann.Clin Psychiatry 2009;21(4):213-236. View abstract. Plioplys AV, Plioplys S. Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. 2009;10(12):1875-1882. View abstract. 2010;66(2):127-136. Saneian H, Khalilian L, Heidari-Beni M, et al. Unexpected awakening from comatose thyroid storm after a single intravenous injection of L-carnitine. Int J Tissue React. L-carnitine is an amino acid derivative that transports fatty acids into your cells to be processed for energy. De Vecchi, A. F., Arduini, A., Di, Liberato L., and Bonomini, M. [L-carnitine in peritoneal dialysis]. Benvenga S, Ruggeri RM, Russo A, et al. View abstract. Weschler, A., Aviram, M., Levin, M., Better, O. S., and Brook, J. G. High dose of L-carnitine increases platelet aggregation and plasma triglyceride levels in uremic patients on hemodialysis. 1979;43(2):300-306. L-carnitine improves glucose disposal in type 2 diabetic patients. El-Beshlawy, A., El, Accaoui R., Abd El-Sattar, M., Gamal El-Deen, M. H., Youssry, I., Shaheen, N., Hamdy, M., El-Ghamrawy, M., and Taher, A. 2006;8(3-4):404-416. Touati, G., Valayannopoulos, V., Mention, K., de, Lonlay P., Jouvet, P., Depondt, E., Assoun, M., Souberbielle, J. C., Rabier, D., Ogier de, Baulny H., and Saudubray, J. M. Methylmalonic and propionic acidurias: management without or with a few supplements of specific amino acid mixture. 12-3-1999;87(4):366-368. Jimenez Caballero, P. E. and Marsal, Alonso C. [Type 1 glutaric aciduria: clinical and therapeutic implications]. Although the recommended dose varies, around 5002,000 mg (0.52 grams) seems to be both safe and effective. However, this does not explain why insomnia actually occurs. Cochrane.Database.Syst.Rev. View abstract. FDA. Bipolar.Disord. Eur.Heart J 2007;28(5):608-612. Shang R, Sun Z, Li H. Effective dosing of L-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis. J Pain Symptom.Manage. View abstract. 2008;54(6):375-381. Tell your doctor if you are pregnant or plan to become pregnant. Randomized phase III clinical trial of five different arms of treatment in 322 patients with cancer cachexia. It plays a crucial role in the production of energy by transporting fatty acids into your cells' mitochondria ( 1, 2, 3 ). Goodison G, Overeem K, de Monte V, Siskind D. Mania associated with self-prescribed acetyl-l-carnitine in a man with bipolar I disorder. Gwak, J. H., Lee, J. H., Lee, S. J., Park, H. W., Kim, Y., and Hyun, Y. J. Written by Cerner Multum. Askarpour M, Hadi A, Miraghajani M, Symonds ME, Sheikhi A, Ghaedi E. Beneficial effects of l-carnitine supplementation for weight management in overweight and obese adults: An updated systematic review and dose-response meta-analysis of randomized controlled trials. Clin Nephrol 2003;59(1):24-30. A case of hemoperfusion and L-carnitine management in valproic acid overdose. Biochem Pharmacol 2003;65:1483-8.. View abstract. Last updated on Aug 31, 2022. I tried this recently at a low dose, 125 mg, and had strong side effects for a day or two. View abstract. Anand I, Chandrashekhan Y, De Giuli F, et al. Nausea and Vomiting The Linus Pauling Institute notes that common side effects of taking L-carnitine supplements are nausea and vomiting 1. View abstract. View abstract. Effects of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: a double-blind crossover field study. Int J Clin Pharmacol Res 1983;3(3):179-184. De Grandis D, Minardi C. Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy. J Pediatr 1982;101:782-5. View abstract. Ruggenenti, P., Cattaneo, D., Loriga, G., Ledda, F., Motterlini, N., Gherardi, G., Orisio, S., and Remuzzi, G. Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy. Phillips, T. J., Cherry, C. L., Cox, S., Marshall, S. J., and Rice, A. S. Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials. 2013 Apr;121(4):234-8. Clin Auton.Res 2000;10(1):13-16. Our website services, content, and products are for informational purposes only. [Ref], Very common (10% or more): Anemia (12%)[Ref], Common (1% to 10%): Kidney failure (chronic hemodialysis patients)[Ref], Common (1% to 10%): Parathyroid disorder[Ref], Very common (10% or more): Pharyngitis (27%), cough increase (18%), dyspnea (11%), rhinitis (11%), Common (1% to 10%): Bronchitis, sinusitis[Ref], Common (1% to 10%): Amblyopia, eye disorder[Ref], Common (1% to 10%): Urinary tract infection[Ref], Very common (10% or more): Hypertension (21%), hypotension (19%), Common (1% to 10%): Atrial fibrillation, arrhythmia, cardiovascular disorder, electrocardiogram abnormal, palpitations, tachycardia, vascular disorder[Ref], Common (1% to 10%): Allergic reaction[Ref], Common (1% to 10%): Depression, anxiety, drug dependence, insomnia[Ref], Very common (10% or more): Infection (24%)[Ref]. 2011;28(4):393-400. Seong, S. H., Cho, S. C., Park, Y., and Cha, Y. S. L-carnitine-supplemented parenteral nutrition improves fat metabolism but fails to support compensatory growth in premature Korean infants. Complement Ther Med 2011;19(4):216-227. insomnia numbness in feet or hands Call your doctor if any of these symptoms persist, or if they get worse. It can also cause the urine, breath, and sweat to have a "fishy" odor. View abstract. Chinese J.Pract.Internal Med. 11. View abstract. 2007;3(3):129-138. J Am Soc Nephrol 2002;13:708-14.. View abstract. Double-blind, randomised, placebo-controlled trial on the effect of L-carnitine and L-acetylcarnitine on sperm parameters in men with idiopathic oligoasthenozoospermia. View abstract. J Inherit.Metab Dis 2008;31 Suppl 2:S453-S456. View abstract. Rockstar zero carb packs a powerful boost but has zero sugar and just 10 carbs per serving. Tabei SM, Mazloom M, Shahriari M, Zareifar S, Azimi A, Hadaegh A, Karimi M. Determining and surveying the role of carnitine and folic acid to decrease fatigue in -thalassemia minor subjects. Serjeant, B. E., Harris, J., Thomas, P., and Serjeant, G. R. Propionyl-L-carnitine in chronic leg ulcers of homozygous sickle cell disease: a pilot study. L-carnitine and Vitamin B Complex for the Treatment of Pegasparaginase-induced Hyperbilirubinemia. Kavukcu, S., Turkmen, M., Salman, S., Onvural, B., Oktay, G., Karaman, O., and Cevik, N. T. The effects of L-carnitine on respiratory function tests in children undergoing chronic hemodialysis. This thread is archived J Med.Toxicol. Cifone MG, Alesse E, Di Marzio L, et al. Benedini, S., Perseghin, G., Terruzzi, I., Scifo, P., Invernizzi, P. L., Del, Maschio A., Lazzarin, A., and Luzi, L. Effect of L-acetylcarnitine on body composition in HIV-related lipodystrophy. Aliment.Pharmacol Ther 2011;34(9):1088-1097. 2007;25(6):611-618. In a person with an overactive thyroid gland, who produces such large quantities of these thyroid hormones that he/she develops a variety of symptoms (including palpitations, increased body temperature, shakiness, irritability, insomnia and weight loss), the inhibiting effects of L-carnitine can be useful (Benvenga, 2005).